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However, there have only been few studies that provide a comparative performance evaluation of different systems on a common database. 17 Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands Fraunhofer MEVIS, Bremen, Germany.Īutomatic detection of pulmonary nodules in thoracic computed tomography (CT) scans has been an active area of research for the last two decades.16 Center of Applied Technologies and Nuclear Development, La Habana, Cuba.15 Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands Department of Radiology, Meander Medisch Centrum, Amersfoort, The Netherlands.14 Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands.13 Department of Electronics and Informatics, Vrije Universiteit Brussel, Brussels, Belgium.12 Centro de Biofísica Médica, Universidad de Oriente, Santiago de Cuba, Cuba.11 Centro de Biofísica Médica, Universidad de Oriente, Santiago de Cuba, Cuba Department of Electronics and Informatics, Vrije Universiteit Brussel, Brussels, Belgium Center of Applied Technologies and Nuclear Development, La Habana, Cuba.10 Yan'an Xi Lu 129, 9th floor, Shanghai, China.9 Department of Electronics and Informatics, Vrije Universiteit Brussel, Brussels, Belgium IMEC, Leuven, Belgium.8 Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.7 Department of Physics, University of Pisa, Pisa, Italy Pisa Section of Istituto Nazionale di Fisica Nucleare, Pisa, Italy.6 Department of Computer Science and Engineering, The Chinese University of Hong Kong, China.5 Turin Section of Istituto Nazionale di Fisica Nucleare, Turin, Italy.4 Radboud University, Nijmegen, The Netherlands.3 Institute for Computing and Information Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.Electronic address: 2 Department of Applied Science and Technology, Polytechnic University of Turin, Turin, Italy Turin Section of Istituto Nazionale di Fisica Nucleare, Turin, Italy Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands. 1 Diagnostic Image Analysis Group, Radboud University Medical Center, Nijmegen, The Netherlands.